Activity Assay:Article Title: Frailty, Implantable Cardioverter Defibrillators, and Mortality: a Systematic Review
Article Snippet: .. Kramer et al. (2015) , Retrospective cohort , Association between physical activity and survival following ICD USA , Boston Scientific LATITUDE remote monitoring system USA , Mean daily activity captured by the accelerometer in the ICD, reported in quintiles , All-cause mortality , 98,437 , Mean age 68, mean age 74.6 in the lowest , 2.2 years (median) , Lower baseline activity was independently associated with an increased risk of death (adjusted HR 1.44, 95% CI 1.427–1.462). .. Green et al. (2016) , Retrospective cohort , Association between frailty and dementia on 1 year mortality following ICD USA , Registry: NCDR and Medicare USA , Variation of the cumulative deficit method: Johns Hopkins coding algorithm incorporating 99 ICD-9 codes indicating 10 geriatric diagnostic clusters , All-cause mortality , 83,972 , Mean age 75 , 1 year , Individuals with frailty had a higher mortality rate compared to the overall cohort (22% vs 12%) Patients with frailty alone had an increased odds of mortality (adjusted OR 4.00 [95% CI not reported]) while those with frailty and dementia had the highest odds of death (adjusted OR 8.68, 95% CI 7.33–10.27) compared to those with no comorbidity.
Article Title: Frailty, Implantable Cardioverter Defibrillators, and Mortality: a Systematic Review
Article Snippet: .. In the lowest tertile of walking speed the benefit was null (HR 1.02, 95%CI 0.75–1.39, p = 0.90) Kramer et al. (2015) Retrospective cohort Association between physical activity and survival following ICD USA Boston Scientific LATITUDE remote monitoring system USA Mean daily activity captured by the accelerometer in the ICD, reported in quintiles All-cause mortality 98,437 Mean age 68, mean age 74.6 in the lowest 2.2 years (median) Lower baseline activity was independently associated with an increased risk of death (adjusted HR 1.44, 95% CI 1.427–1.462) Green et al. (2016) Retrospective cohort Association between frailty and dementia on 1 year mortality following ICD USA Registry: NCDR and Medicare USA Variation of the cumulative deficit method: Johns Hopkins coding algorithm incorporating 99 ICD-9 codes indicating 10 geriatric diagnostic clusters All-cause mortality 83,972 Mean age 75 1 year Individuals with frailty had a higher mortality rate compared to the overall cohort (22% vs 12%) Patients with frailty alone had an increased odds of mortality (adjusted OR 4.00 [95% CI not reported]) while those with frailty and dementia had the highest odds of death (adjusted OR 8.68, 95% CI 7.33–10.27) compared to those with no comorbidity Gostoli et al. (2016) Prospective cohort Association between allostatic overload and ICD mortality Department of Cardiology, University of Bologna, Bologna, Italy Allostatic overload: poor baseline psychological and psychosomatic profile All-cause mortality 117 Mean age 63.1 Up to 24 months Patients with severe allostatic overload are less likely to survive (HR 0.18, 95% CI 0.06–0.51, p < 0.001) Jahangir et al. (2017) Retrospective cohort Association between BMI and outcomes following ICD implantation Aurora Health Care system in Milwaukee, Wisconsin USA Low BMI All-cause mortality 904 Mean age 67 Mean 2.6 years Obese (10.1%, OR 0.35, 95% CI 0.21–0.58) and overweight (7.9%, OR 0.25, 95% CI 0.13–0.40) groups had lower mortality than the normal group (22.9%, p < 0.001) Open in a separate window ICD implantable cardioverter defibrillator, BMI body mass index, OR odds ratio, CI confidence interval, RCT randomized controlled trial, SCD-HEFT Sudden Cardiac Death in Heart Failure Trial, HR hazard ratio Participant Characteristics and Frailty-Outcome Results From Included Studies The two RCTs included both used a marker of physical activity to assess frailty and found that low physical activity, either by self-report or measured was associated with increased risk of mortality. ..
Infection:Article Title: Full Issue PDF
Article Snippet: .. We report the case of a patient who tested positive for severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection and who was implanted with an ICD (AUTOGEN X4 cardiac resynchronization therapy defibrillator; Boston Scientific, St. Paul, Minnesota) equipped with respiratory rate trend (RRT), a diagnostic algorithm for continuous respiratory rate (RR) monitoring and followed-up with the LATITUDE (Boston Scientific) remote monitoring system. ..
Diagnostic Assay:Article Title: Full Issue PDF
Article Snippet: .. We report the case of a patient who tested positive for severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection and who was implanted with an ICD (AUTOGEN X4 cardiac resynchronization therapy defibrillator; Boston Scientific, St. Paul, Minnesota) equipped with respiratory rate trend (RRT), a diagnostic algorithm for continuous respiratory rate (RR) monitoring and followed-up with the LATITUDE (Boston Scientific) remote monitoring system. ..
Article Title: Frailty, Implantable Cardioverter Defibrillators, and Mortality: a Systematic Review
Article Snippet: .. In the lowest tertile of walking speed the benefit was null (HR 1.02, 95%CI 0.75–1.39, p = 0.90) Kramer et al. (2015) Retrospective cohort Association between physical activity and survival following ICD USA Boston Scientific LATITUDE remote monitoring system USA Mean daily activity captured by the accelerometer in the ICD, reported in quintiles All-cause mortality 98,437 Mean age 68, mean age 74.6 in the lowest 2.2 years (median) Lower baseline activity was independently associated with an increased risk of death (adjusted HR 1.44, 95% CI 1.427–1.462) Green et al. (2016) Retrospective cohort Association between frailty and dementia on 1 year mortality following ICD USA Registry: NCDR and Medicare USA Variation of the cumulative deficit method: Johns Hopkins coding algorithm incorporating 99 ICD-9 codes indicating 10 geriatric diagnostic clusters All-cause mortality 83,972 Mean age 75 1 year Individuals with frailty had a higher mortality rate compared to the overall cohort (22% vs 12%) Patients with frailty alone had an increased odds of mortality (adjusted OR 4.00 [95% CI not reported]) while those with frailty and dementia had the highest odds of death (adjusted OR 8.68, 95% CI 7.33–10.27) compared to those with no comorbidity Gostoli et al. (2016) Prospective cohort Association between allostatic overload and ICD mortality Department of Cardiology, University of Bologna, Bologna, Italy Allostatic overload: poor baseline psychological and psychosomatic profile All-cause mortality 117 Mean age 63.1 Up to 24 months Patients with severe allostatic overload are less likely to survive (HR 0.18, 95% CI 0.06–0.51, p < 0.001) Jahangir et al. (2017) Retrospective cohort Association between BMI and outcomes following ICD implantation Aurora Health Care system in Milwaukee, Wisconsin USA Low BMI All-cause mortality 904 Mean age 67 Mean 2.6 years Obese (10.1%, OR 0.35, 95% CI 0.21–0.58) and overweight (7.9%, OR 0.25, 95% CI 0.13–0.40) groups had lower mortality than the normal group (22.9%, p < 0.001) Open in a separate window ICD implantable cardioverter defibrillator, BMI body mass index, OR odds ratio, CI confidence interval, RCT randomized controlled trial, SCD-HEFT Sudden Cardiac Death in Heart Failure Trial, HR hazard ratio Participant Characteristics and Frailty-Outcome Results From Included Studies The two RCTs included both used a marker of physical activity to assess frailty and found that low physical activity, either by self-report or measured was associated with increased risk of mortality. ..
Marker:Article Title: Frailty, Implantable Cardioverter Defibrillators, and Mortality: a Systematic Review
Article Snippet: .. In the lowest tertile of walking speed the benefit was null (HR 1.02, 95%CI 0.75–1.39, p = 0.90) Kramer et al. (2015) Retrospective cohort Association between physical activity and survival following ICD USA Boston Scientific LATITUDE remote monitoring system USA Mean daily activity captured by the accelerometer in the ICD, reported in quintiles All-cause mortality 98,437 Mean age 68, mean age 74.6 in the lowest 2.2 years (median) Lower baseline activity was independently associated with an increased risk of death (adjusted HR 1.44, 95% CI 1.427–1.462) Green et al. (2016) Retrospective cohort Association between frailty and dementia on 1 year mortality following ICD USA Registry: NCDR and Medicare USA Variation of the cumulative deficit method: Johns Hopkins coding algorithm incorporating 99 ICD-9 codes indicating 10 geriatric diagnostic clusters All-cause mortality 83,972 Mean age 75 1 year Individuals with frailty had a higher mortality rate compared to the overall cohort (22% vs 12%) Patients with frailty alone had an increased odds of mortality (adjusted OR 4.00 [95% CI not reported]) while those with frailty and dementia had the highest odds of death (adjusted OR 8.68, 95% CI 7.33–10.27) compared to those with no comorbidity Gostoli et al. (2016) Prospective cohort Association between allostatic overload and ICD mortality Department of Cardiology, University of Bologna, Bologna, Italy Allostatic overload: poor baseline psychological and psychosomatic profile All-cause mortality 117 Mean age 63.1 Up to 24 months Patients with severe allostatic overload are less likely to survive (HR 0.18, 95% CI 0.06–0.51, p < 0.001) Jahangir et al. (2017) Retrospective cohort Association between BMI and outcomes following ICD implantation Aurora Health Care system in Milwaukee, Wisconsin USA Low BMI All-cause mortality 904 Mean age 67 Mean 2.6 years Obese (10.1%, OR 0.35, 95% CI 0.21–0.58) and overweight (7.9%, OR 0.25, 95% CI 0.13–0.40) groups had lower mortality than the normal group (22.9%, p < 0.001) Open in a separate window ICD implantable cardioverter defibrillator, BMI body mass index, OR odds ratio, CI confidence interval, RCT randomized controlled trial, SCD-HEFT Sudden Cardiac Death in Heart Failure Trial, HR hazard ratio Participant Characteristics and Frailty-Outcome Results From Included Studies The two RCTs included both used a marker of physical activity to assess frailty and found that low physical activity, either by self-report or measured was associated with increased risk of mortality. ..
other:Article Title: Subcutaneous versus transvenous implantable defibrillator in patients with hypertrophic cardiomyopathy.
Article Snippet: BACKGROUND Hypertrophic cardiomyopathy (HCM) is the most prevalent inherited cardiomyopathy.. The implantable cardioverter-defibrillator (ICD) is important for prevention of sudden cardiac death (SCD) in patients at high risk.. In recent years, the subcutaneous implantable cardioverter-defibrillator (S-ICD) has emerged as a viable alternative to the transvenous implantable cardioverter-defibrillator (TV-ICD).
Diffusion-based Assay:Article Title: How Well Do Results From Randomized Clinical Trials and/or Recommendations for Implantable Cardioverter‐Defibrillator Programming Diffuse Into Clinical Practice?
Article Snippet: .. Potentially, these could be leveraged to reveal shifts in practice.11 Therefore, we used the ALTITUDE database of Boston Scientific ICD and CRT-Ds followed on the LATITUDE remote monitoring system to measure the influence of 2 separate landmark publications (namely, the MADIT-RIT trial and then consensus recommendations), hypothesizing that diffusion of trial results for ICD programming into the general US population would occur slowly and be incomplete. .. The design and methods of the ALTITUDE research program to prospectively analyze data from implanted ICD and CRT-Ds have been described previously.12 Briefly, beginning in 2006, the ALTITUDE study has been updated with data from the LATITUDE US remote monitoring system (Boston Scientific, Marlborough, MA) for clinical research purposes.
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